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VPC-80051 racemate
CAS No. 877969-69-2
VPC-80051 racemate( VPC-80051 )
Catalog No. M28584 CAS No. 877969-69-2
VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 87 | Get Quote |
|
| 5MG | 147 | Get Quote |
|
| 10MG | 250 | Get Quote |
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| 25MG | 537 | Get Quote |
|
| 50MG | 767 | Get Quote |
|
| 100MG | 1053 | Get Quote |
|
| 500MG | 2115 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameVPC-80051 racemate
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NoteResearch use only, not for human use.
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Brief DescriptionVPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.
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DescriptionVPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.(In Vitro):VPC-80051 interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line.
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In VitroVPC-80051 interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line. hnRNP A1 is a multifunctional RNA-binding protein that regulates alternative pre-mRNA splicing, transcription, nucleocytoplasmic shuttling, miRNA processing, and telomere elongation maintenance, as well as translation of cellular transcripts both in physiological and pathological conditions.
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In Vivo——
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SynonymsVPC-80051
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number877969-69-2
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Formula Weight301.29
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Molecular FormulaC16H13F2N3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (331.91 mM)
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SMILESCC(c(cc1)cc(F)c1F)NC(c1n[nH]c2c1cccc2)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Fan X, Xu NJ, Shi JG. Bromophenols from the red alga Rhodomela confervoides. J Nat Prod. 2003 Mar;66(3):455-8.
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